题目

英语翻译
Patient characteristics:Baseline patient characteris-tics were very similar among groups.Table 1 shows characteristics by drug assignment.Of the 2,431 pa-tients randomized to treatment,94% completed the 6-week trial (Figure 1).Drug compliance as assessed by tablet counts was similar among treatments,and means of tablets taken ranged from 90.5% to 95.3%.
Efficacy:According to the dose-response analyses,mean differences between the LDL cholesterol dose-response slopes of rosuvastatin 10 to 80 mg versus atorvastatin 10 to 80 mg and pravastatin 10 to 40 mg were significant (both p 0.001) (Figure 2).The log- dose slopes of rosuvastatin and simvastatin were not parallel,but equivalent doses were significantly dif- ferent (Figure 2).All differences that were 6% were considered clinically significant.
In the pairwise,dose-to-dose comparisons with atorvastatin,rosuvastatin 10 mg reduced LDL choles- terol significantly more than atorvastatin 10 mg,rosu- vastatin 20 mg reduced LD

提问时间：2020-11-02

答案

特点:基线患者多种病人非常相似人群.表1所示为特征的药物分配.2,431的pa-tients随机分为两组,一组治疗,94%完成了六周试验(图1).药物依从的平板计数是相似的,在治疗手段,采取从90.5%版95.3%.
功效:根据各个区别分析,平均剂量的低密度脂蛋白胆固醇)10至80斜坡和10至80毫克阿普10毫克到40毫克显著(p 0.001)(图2).日志-剂量的斜坡上)和辛伐他汀不平行,但等效剂量显著见dis -不同(图2).所有的不同点是6%被认为是临床显著.
在其中,dose-to-dose比较阿托伐他汀、降低低密度脂蛋白(LDL)choles 10毫克)——terol明显多于10毫克阿,rosu - vastatin 20毫克降低低密度脂蛋白胆固醇明显多于阿托伐他汀20至40毫克,)
40毫克降低低密度脂蛋白胆固醇明显多于阿托伐他汀40毫克(表2).在几乎所有其他的阿托伐他汀(rosuv两两比较astatin 10节——阿托伐他汀40毫克),duced亲)数值更低密度脂蛋白胆固醇reduc),但这些差异,并没有明显见dis -不同(表2).降低低密度脂蛋白胆固醇)显著高于辛伐他汀和普两两比较分析了在所有14(表2).最好的低密度脂蛋白胆固醇(55%)就40-mg)集团和无明显差异(p 0.006)从隔壁的最高的低密度脂蛋白胆固醇(51%)中观察到的阿托伐他汀80-mg集团.